Scientific Sessions

Neuroscience of Addiction and Behavioral Disorders

The neuroscience of addiction reveals how repeated exposure to addictive substances or behaviors alters brain circuits related to reward, motivation, and self-control. Substances such as alcohol, opioids, or stimulants stimulate the brain’s reward system by releasing excess dopamine, reinforcing the cycle of craving and use. Over time, these neurochemical changes weaken decision-making pathways in the prefrontal cortex while strengthening conditioned responses in the limbic system, making it difficult to resist triggers. Similarly, behavioral addictions such as gambling, gaming, and compulsive internet use activate the same neural mechanisms, highlighting the brain’s vulnerability to both chemical and non-chemical stimuli.

Behavioral disorders connected to addiction extend beyond the pleasure-seeking cycle and involve disruptions in stress regulation, impulse control, and emotional processing. Neuroscientific studies show that genetic predisposition, environmental stressors, and early-life experiences contribute to these vulnerabilities. Advances in neuroimaging and brain mapping now allow researchers to observe these changes in real time, providing insights for targeted interventions. Treatments combining medication, cognitive-behavioral therapy, and neuromodulation techniques aim to restore brain balance and improve self-regulation. By understanding the neural underpinnings of addiction and behavioral disorders, neuroscience paves the way for more precise therapies, prevention strategies, and long-term recovery solutions that address both the biological and psychological dimensions of these conditions.